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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN9
All Species:
18.18
Human Site:
T452
Identified Species:
36.36
UniProt:
P43378
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43378
NP_002824.1
593
68020
T452
T
T
L
E
I
H
N
T
E
E
R
Q
K
R
Q
Chimpanzee
Pan troglodytes
XP_001144390
596
67599
T455
T
T
L
E
I
H
N
T
E
E
R
Q
K
R
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854411
607
69728
T466
T
T
L
E
I
H
N
T
E
E
R
Q
K
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35239
593
67952
T452
T
T
L
E
I
H
N
T
E
E
R
Q
K
R
Q
Rat
Rattus norvegicus
Q641Z2
593
67944
T452
T
T
L
E
I
H
N
T
E
E
R
Q
K
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505361
613
70033
P472
T
V
L
E
I
H
N
P
E
D
R
E
R
R
R
Chicken
Gallus gallus
XP_413696
584
66275
A443
T
I
L
E
I
H
S
A
E
V
G
R
E
R
R
Frog
Xenopus laevis
NP_001081203
694
79518
K550
T
H
F
E
V
Y
N
K
Q
T
D
E
S
R
S
Zebra Danio
Brachydanio rerio
XP_001923429
571
65239
Q430
D
N
H
A
H
Y
N
Q
T
T
L
E
L
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727356
797
85738
I652
A
S
L
E
L
R
N
I
K
T
D
E
I
R
N
Honey Bee
Apis mellifera
XP_394701
660
73346
K514
S
M
L
L
L
T
N
K
K
T
D
E
A
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200442
281
32148
R141
S
T
T
N
E
S
R
R
I
T
H
F
Q
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
N.A.
92
N.A.
97.3
97.1
N.A.
75.8
74
44.3
67.7
N.A.
35.6
43.4
N.A.
25.8
Protein Similarity:
100
94.6
N.A.
94.4
N.A.
98.6
98.9
N.A.
87.4
84.4
61
81.6
N.A.
49.1
60.6
N.A.
34.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
60
46.6
26.6
6.6
N.A.
26.6
20
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
73.3
53.3
20
N.A.
53.3
53.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
9
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
9
25
0
0
0
0
% D
% Glu:
0
0
0
75
9
0
0
0
59
42
0
42
9
0
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
9
9
0
9
59
0
0
0
0
9
0
0
9
0
% H
% Ile:
0
9
0
0
59
0
0
9
9
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
17
0
0
0
42
0
0
% K
% Leu:
0
0
75
9
17
0
0
0
0
0
9
0
9
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
0
0
84
0
0
0
0
0
0
0
17
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
9
0
0
42
9
0
42
% Q
% Arg:
0
0
0
0
0
9
9
9
0
0
50
9
9
84
17
% R
% Ser:
17
9
0
0
0
9
9
0
0
0
0
0
9
0
9
% S
% Thr:
67
50
9
0
0
9
0
42
9
42
0
0
0
0
9
% T
% Val:
0
9
0
0
9
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _